MEPS Syringes


MEPS is Micro Extraction by Packed Sorbent and is a development for sample preparation and handling. MEPS is the miniaturization of conventional SPE packed bed devices from milliliter bed volumes to microliter volumes. The MEPS approach to sample preparation is suitable for reversed phases, normal phases, mixed mode or ion exchange chemistries. MEPS is available in a variety of common SPE phases.


The MEPS Barrel Insert and Needle (BIN) assembly contains the stationary phase, and is built into the syringe needle.


TSample volumes may be as little as 10 μL, or by taking multiple aliquots of 100 μL or 250 μL, samples of 1 mL or larger may be concentrated.


Extract samples and make injections on-line using a single device, reducing sample processing times and the need for operator intervention.


EBIN life is dependent on the specific matrix being analyzed. For example, C18 analysis of whole plasma samples is conservatively 25-100 samples before the BIN needs to be changed. BIN life of cleaner samples is significantly longer.

Chromatogram of 22 pesticides standard solution (40 ng/mL)


The small quantity of phase in the MEPS BIN is easily and effectively washed between samples to reduce the possibility of carryover. This washing process is not practical with off-line SPE devices. With automation of MEPS, washing occurs while the previous sample is running.


The dimensions of the sorbent bed ensure performance remains identical to conventional SPE devices when used for extraction of similar samples. The AOC-MEPS system was developed to incorporate MEPS into a process automation workflow, combining sample preparation and analysis in a single platform


When automated by AOC-MEPS system, the injection volume is much larger compared to the commonly used GC injection volumes of 1 - 2 μL. With AOC-MEPS, the typical injections are 50 to 200 μL of elution solvent into the analytical instrument. A large volume injection volume technique should be employed that removes the solvent volume from inside the injector unit while condensing the target compounds.

PTV Inlet Liner for AOC-MEPS System
(AOC-20i + GC-2010 + PTV configuration)

OD (mm) ID (mm) Length (mm) P/N
3.5 2.5 95 221-74830-09


MEPS Syringe for AOC-20i/20s
  Replacement Punger
Syringe Volume PTFE Tipped Plunger P/N Qty P/N
100 μL 221-74830-01 1 221-74830-10
Phase Qty per pack P/N
C18 5 221-74830-03
Silica 5 221-74830-04
C8 + SCX 5 221-74830-05
C2 5 221-74830-06
C8 5 221-74830-07
PDVB 5 221-74830-02
SDVB 5 221-74830-11
HDVB 5 221-74830-12
Development Kit - contains 1 each of C18, C8, Silica, C8+SCX, C2 1 of each phase 221-74830-08


MEPS Syringes for AOC-5000
  Replacement Plunger
Syringe Volume PTFE Tipped Plunger P/N Qty P/N
100 μL 221-75202-01 1 221-75202-03
250 μL 221-75202-02 1 221-75202-04
Phase Qty per pack MEPS for 100 μL Syringe P/N MEPS for 250 μL Syringe P/N
C18 5 221-75198-01 221-75199-01
Silica 5 221-75198-02 221-75199-02
C8 + SCX 5 221-75198-03 221-75199-03
C2 5 221-75198-04 221-75199-04
C8 5 221-75198-06 221-75199-06
Development Kit - contains 1 each of
C18, C8, Silica, C8+SCX, C2
1 of each phase 221-75198-05 221-75199-05

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